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Laboratory news

2

2010 JINR Prizes
21 September 2011

The 2010 JINR Prize winners are announced. The second prize for applied research is awarded to LRB's scientists M. A. Ostrovskiy, Kh. T. Kholmurodov, T. B. Feldman. for their work "Application of the molecular dynamics method to studying the dark-adapted condition of the light-sensitive protein rhodopsin of the retinal visual cells."


The books by Prof. Kh.T. Kholmurodov
29 June 2011

 

The book of "Molecular Dynamics of Nanobistructures" (Ed. Kholmirzo Kholmurodov) is now available as hardcover in its final production.

A book on teaching of the methodology and application aspects of molecular dynamics (MD) simulation for the master-graduate and PhD students of International University "Dubna" has been written in Russian and in English by Prof. Kholmirzo Kholmurodov.

A new book "Homology Modelling and Molecular Dynamics of Cyclin-Dependent Protein Kinases" by Robert A. Selwyne, Kholmirzo T. Kholmurodov, Natalia A. Koltovaya, has been published by IT for Real Rorld Problems, (Universities Press Series in Systems, Models, Informatics and Control), Ed. Sree Hari Rao (Ed.), pp. 1-72.

 


Medal Awarding
17.04.2011

LRB Director Prof. E.A. Krasavin and Deputy Director for Science Prof. G. N. Timoshenko received medals "Yuriy Alekseevich Gagarin" from the Astronautics Federation of Russia for their great personal contribution to the development of astronautics in Russia. R. D. Govorun received a medal "Preodolenie" from the Space Association of Museums of Russia.

 

 

 

 

 

 


Round table "Topical Issues of Radiation Safety of Long-Term Space Flights"
26 April 2011

The round table "Topical Issues of Radiation Safety of Long-Term Space Flights" timed to the 50th anniversary of the first manned space flight was held in Dubna. Its subjects included modeling the effect of heavy charged particles of the space origin on biological objects; radiation and radiobiological aspects of long-term manned space flights; and radiation safety of manned space missions.

Dubna TV report, 27 April 2011

Download (wmv, 23 Mb)

Dubna TV report, 26 April 2011, timed to the 25th anniversary of the Cernobyl nuclear power plant disaster.

Download (wmv, 13 Mb)


A letter of commendation
13 April 2011

LRB Director Prof. E.A. Krasavin received a letter of commendation from the Russian Federation's Ministry of Education and Science for his great personal contribution to the development of science in Russia and for his committed work over many years.

PDF


JINR and stages of the great way in space
14 April 2011

The weekly "Dubna: nauka, sodruzhestvo, progress" ("Dubna: Science, Cooperation, Progress") published on 8 April 2011, pp. 67, an interview with LRB Director Prof. E.A. Krasavin about the participation of JINR's biologists and physicists in different stages of space exploration. An electronic version of the interview is available on the LRB site.

Download an electronic version (in Russian)


Before flying to Mars
31 March 2011

The "Vesti Dubny" newspaper published on 31 March 2011, p. 5, an interview with LRB Director Prof. E.A. Krasavin timed to the 50th anniversary of the first manned space flight. The electronic version of the issue is available on the LRB site.

Download an electronic version (in Russian)


Round table "Actual radiation safety questions of long-term space flights" (50th anniversary of the first manned space flight)
14 March 2011

On 2526 April 2011, JINR, in cooperation with a number of institutes, holds the Round Table "Actual radiation safety questions of long-term space flights" to mark the 50th anniversary of the first manned space flight.

The meeting will focus on the following topics:

  1. Modeling the effect of heavy charged particles of space origin on biological objects (at the molecular, cellular, tissue, and organism levels).
  2. Radiation and radiobiological aspects of long-term manned space flights.
  3. Measures to provide radiation safety of long-term space flights.

The Round Table's web site: http://lrb.jinr.ru/spacebio2011/ (switch page to English)


MSSMBS'10 proceedings
5 March 2011

The Nova Science Publishers (New York) issued a book edited by Prof. Kh.T. Kholmurodov and entitled "Molecular Dynamics of Nanobiostructures." The book contains proceedings of the 4th Russian Japanese workshop "Molecular Simulation Studies in Material and Biological Sciences" (2629 September 2010), which is regularly organized by the LRB, JINR, in cooperation with its Japanese colleagues and the Chemical Faculty of Moscow State University.


LRB seminar
2 March 2011

I.K. Khvostunov, Cand. Biol., presented a report entitled "The role of the stochastic factors during the formation of the primary DNA lesions and chromosome aberrations under the effect of radiation on mammalian somatic cells in vitro and in vivo." The author is going to submit this work as a doctoral thesis in the specialty of radiobiology (03.01.01). For thesis defense, the LRB has been recommended as the supervising organization.


LRB Scientific and Technical Council
22 February 2011

On 22 February 2011, a meeting of the LRB Scientific and Technical Council was held where T.B. Feldman, Cand. Biol., presented the main points of her work entitled "Photochemistry and molecular dynamics of the visual pigment rhodopsin." This work will be submitted as a doctoral thesis in the specialty of biophysics (03.00.02). For thesis defense, the LRB has been recommended as the supervising organization.


LRB seminar
27 January 2011

On 27 January 2011, a seminar was held at the LRB where Prof. Latchezar Avramov of the Institute of Electronics, the Bulgarian Academy of Sciecnes, made a report entitled "Biophotonics technologies in anticancer therapy."


All-JINR seminar "Life and Biosphere on the Early Earth"
26 January 2011

On 26 January 2011, an all-JINR seminar entitled "Life and Biosphere on the Early Earth" was held at the Conference Hall of the Bogoliubov Laboratory of Theoretical Physics. The talk was given by A.Yu. Rozanov, Academician Secretary of the Section of Biological Sciences, the Russian Academy of Sciences (RAS); a member of the RAS Presidium; Vice President of the Paleontological Society of Russia; and Director of the A.A. Borisyak Paleontological Institute, RAS.

Download a presentation (PowerPoint, 28 Mb)


NASA award
14 October 2010

The JINR staff members V.N. Shvetsov (Laboratory of Neutron Physics), G.N. Timoshenko, and A.R. Krylov (the two latter are of the Laboratory of Radiation Biology), who participated in the working group on the development and fabrication of the Russian-made Lunar Exploration Neutron Detector (LEND) for the NASA Lunar Reconnaissance Orbiter (LRO) have been awarded NASA letters of commendation for the successful completion of the LRO mission.

The main aims of the mission were the global mapping of the Moon, radiation environment exploration, and potential resource (first of all, water ice) prospecting. LEND, which is a collimated neutron detector, is designed for mapping the distribution of hydrogen in the upper (1 m) layer of lunar regolith with a resolution of up to 10 km and for collecting information on the neutron component of circumlunar radiation in the energy range up to 15 MeV. The detector was designed at the Institute of Space Research of the Russian Academy of Sciences under the direction of I.G. Mitrofanov according to an agreement between the Russian Federal Space Agency and NASA. JINR's tasks included the mathematical modeling of the LEND counting response, participation in designing the detector's physical scheme, and preparation and performance of the calibration of the detector samples using natural and artificial neutron sources and a table simulator.

The rocket with the satellite was launched on 18 June 2009; on 15 September, LEND started mapping the lunar surface to search for water ice. In particular, local high hydrogen concentration areas were found in the neighborhood of the crater Cabeus near the Moon's South Pole. Later, two NASA spacecraft struck at the lunar surface in that area; the dust cloud raised by the hits was studied. The analysis of the data of this experiment revealed the presence of an observable amount of water in the cloud.



 

20th International Baldin Seminar
14 October 2010

The 20th International Baldin Seminar on High Energy Physics Problems "Relativistic Nuclear Physics and Quantum Chromodynamics" organized by the Joint Institute for Nuclear Research was held on October 49, 2010, in Dubna. As part of the section "Accelerator facilities: status and perspectives. Progress in experimental studies at the high energy accelerators," the Director of the Laboratory of Radiation Biology Prof. E.A. Krasavin made a report entitled "Biological Effect of Accelerated Heavy Ions," in which the main fields of LRB's research performed at JINR's accelerators are considered.

The Seminar web site


Round Table 2 Italy-Russia@Dubna on "SPACE, PHYSICS, and BIOLOGY"
30 September 2010

We are pleased to announce Round Table 2 Italy-Russia@Dubna on "SPACE PHYSICS and BIOLOGY" (19-22 December, 2010). This Round Table is organized within the framework of the 2010 program of activities of the Scientific Counselor of the Italian Embassy in the Russian Federation; it is approved and financed by the Italian Ministry of Foreign Affairs. The co-organizers of the Round Table are Prof. E.A. Krasavin, Director of the Laboratory of Radiation Biology at the Joint Institute for Nuclear Research, and Prof. A.S. Sorin, Deputy Director of the Bogoliubov Laboratory of Theoretical Physics at the Joint Institute for Nuclear Research. Scientific support is offered by the Russian Academy of Sciences.

(!) All participants have to fill the Registration Form at the Round Table web site.

The Round Table web site


MSSMBS 2010 International Workshop
30 September 2010

On September 26 29, the Laboratory of Radiation Biology of the Joint Institute for Nuclear Research and the Chemistry Faculty of Moscow State University successfully conducted the 4th Japan Russia International Workshop MSSMBS-2010 "Molecular Simulation Studies in Material and Biological Sciences" (co-chaired by Profs. Kholmirzo T. Kholmurodov and Alexander V. Nemukhin). The two-day MSSMBS-2010 loaded scientific program, which included events in Dubna and Moscow, provided a lot of interesting talks on different aspects of materials science and biological research and outlined the current state and prospects of computer molecular simulation studies. The MSSMBS-2010 scientific program covered a broad spectrum of problems in modern physics, biochemistry, and nanotechnology. In particular, the following topics were discussed: first-principles calculations and synchrotron radiation analysis of functional materials; hydrated lipid bilayers; DNA nano-bioelectronics; grapheme-graphane mixing nanostructures; generalized-ensemble simulations in protein science; the atomic theory of nucleation in solids and liquids; specific features of MD simulations of peptides, proteins, and membranes; MD simulations of human red blood cells; studies of nematic liquid crystals; density-functional-based molecular dynamics simulations of disordered materials; ab initio models of electronic states; and so on. The MSSMBS-2010 participants represented leading computer molecular simulation research groups of Japan (Waseda University, Nagoya University, Keio University, Kumamoto University, etc.) and Russia (the Institute of Mathematical Problems of Biology, Pushchino Scientific Center, M.V. Lomonosov Moscow State University, Emanuel Institute of Biochemical Physics, RAS, etc.).

The MSSMBS'10 photoalbum


21st Congress of Pavlov Physiological Society
26 September 2010

On 19 25 September, 2010, in the city of Kaluga, the 21st Congress of Pavlov Physiological Society was held. The main organizers included Pavlov Physiological Society; the Section of Biological Sciences of the Russian Academy of Sciences (RAS); the Kaluga Region Government; the Kaluga City Administration; the Institute of Medical and Biological Problems, RAS; and the Kaluga branch of the Russian State Agrarian University (Timiryazev Moscow Agricultural Academy). The congress program covered a broad range of topics: from molecular and cell biology to entire organism physiology; specific issues of teaching physiology; applied and innovative aspects of physiology, neuroinformatics, nanobiotechnologies, and bioethics; and more. As part of the Congress, the symposium "Molecular and Physiological Aspects of the Effect of Ionizing Radiation" was organized, which was held under the chairmanship of Prof. E.A. Krasavin. The symposium was actively participated by a number of scientists of the Laboratory of Radiation Biology, JINR.

The site of the Congress


Problems of Biochemistry, Radiobiology, and Space Biology
20 September 2010

On 5 9 September, the Fourth Sissakian Readings were held at JINR's "Alushta" boarding house. This event was organized by the Joint Institute for Nuclear Research, Russian Academy of Sciences (RAS); A.N. Bach Institute of Biochemistry, RAS; Institute of Medical and Biological Problems, RAS; National Academy of Sciences of the Republic of Armenia (NAS RA); G.Kh. Bunatian Institute of Biochemistry, NAS RA; Yerevan State University and Dubna University.

The conference became a traditional place of meetings between radiobiologists, biochemists, and specialists in space biology and medicine of different institutes and countries. Due to this year's circumstances, the Readings were held in memory of two outstanding scientists: the father and son Norair Sissakian and Alexei Sissakian. The conference participants came from Armenia, Belarus, Canada, Germany, Italy, Ukraine, and Russia. Altogether, there were 50 registered participants. 13 plenary, 14 section, and 23 poster reports were made.

The conference's results were summed up in the round-table discussion "Acad. N.M. Sissakian's Scientific Heritage and Modern Problems of Radiation and Space Biology," which was held under the chairmanship of Acad. RAS M.A. Ostrovsky and Prof. E.A. Krasavin. In conclusion of the conference, the head of the Organizing Committee Prof. E.A. Krasavin noted once more the unique interdisciplinary character of the conference and the breadth of the topics concerned: from space to agriculture, which nicely corresponds to the scientific heritage and encyclopedic character of N.M. Sissakian's knowledge. He also pointed out the necessity of holding future meetings of this kind on a broader scale that would involve not only biologists and chemists, but also physicists.



The latest issue of the international journal Natural Science
31 August 2010

The paper by Kholmirzo Kholmurodov, Guzel Aru, and Kenji Yasuoka "Molecular dynamics simulations of the interaction of carbon nanotube and a carbon disulfide solvent" is published in the latest issue of the international journal Natural Science.

Download the paper

http://www.scirp.org/journal/ns/

http://www.scirp.org/Journal/Abstract.aspx?paperID=2436&JournalID=69


The latest issue of The Open Chemical Physics Journal
30 August 2010

The latest issue of The Open Chemical Physics Journal has published the contribution paper "Molecular Dynamics Study of the Effect of Electrostatic Interactions on the Biphenyl Structure in the Active HNO3 Solvent," pp.10-16 (7), authored by Kholmirzo Kholmurodov, Alena Chulkova, and Kenji Yasuoka.

Download the paper

http://www.bentham.org/open/tocpj/

http://www.bentham.org/open/topcj/openaccess2.htm

http://www.bentham-open.org/pages/content.php?TOPCJ/2010/00000004/00000001/10TOPCJ.SGM


The latest issue of ABB
16 August 2010

The latest issue of Advances in Bioscience and Biotechnology (ABB) has been released, in which the paper by Kh. Kholmurodov, M. Abasheva, and K. Yasuoka "Molecular dynamics simulations of valinomycin interactions with potassium and sodium ions in water solvent" is published.

The paper abstract

Download the paper

www.scirp.org/journal/abb


MSSMBS 2010 International Workshop
10 August 2010

The 4th Japan-Russia International workshop MSSMBS'10 "Molecular Simulation Studies in Material and Biological Sciences" will be held in Dubna and at MSU, Moscow, on September 26-29 2010.

More...

Download the MSSMBS'10 Final Program

Download the Book of Abstracts


An interview with the LRB Director
13 May 2010

In the April 2010 issue of the Russian-language journal "Tekhnika molodyozhi" ("Technology for the Youth," p. 2), an interview is published with the LRB Director Prof. E.A. Krasavin, Dr. Biol. An electronic version of the issue is available at the LRB site.


Download the electronic version of the April issue of the journal "Tekhnika molodyozhi"


IV SISSAKIAN READINGS "Problems of Biochemistry, Radiation, and Space Biology"
28 April 2010

IV SISSAKIAN READINGS "Problems of Biochemistry, Radiation, and Space Biology" will be held on 5 9 September 2010 in Alushta (Ukraine) at JINR's "Dubna" holiday house.

The site of the Readings


Workshop "Application of Charged Particle Accelerators in Studying Radiation Damage in Systems with a High Level of Organization"
26 April 2010

On 29 30 March 2010, a workshop "Application of Charged Particle Accelerators in Studying Radiation Damage in Systems with a High Level of Organization (Space, Medical, Biological, and Technical Aspects)" was held in Dubna. The following topics were considered: modeling the effect of heavy charged particles of the solar and galactic cosmic rays on biological objects at the cellular, tissue, and organism levels; using heavy charged particle beams for malignant tumor therapy; and modeling radiation damage and failures of microelectronic elements induced by cosmic radiation. The results of the Workshop are summed up in a Memorandum, which is available online.

Download the Workshop's Memorandum

The Workshop's site


1st Announcement MSSMBS'10
31 March 2010

4th Japan-Russia International Workshop MSSMBS 2010 "Molecular Simulation Studies in Material and Biological Sciences," September 26 29, JINR MSU, Dubna, Moscow Region, Russia

We hereby kindly invite you to participate in the 4th Japan Russia International Workshop "Molecular Simulation Studies in Material and Biological Sciences" (MSSMBS 2010) to be organized by JINR, Dubna, September 26 29, in cooperation with the Chemistry Faculty of Moscow State University (Co-Chairman: Prof. Alexander V. Nemukhin).

Although the MSSMBS'10 Preliminary Program has now been compiled, we greatly welcome new speakers and presentation titles. For potential speakers, the MSSMBS'10 Preliminary Program is attached below. Please, check the details of your talk and let us know about the changes and additions you would like to make, if any.

We have already reached agreements on publishing the MSSMBS'10 Proceedings and Collected Abstracts.

 

Download MSSMBS'10 Preliminary Program

MSSMBS 2010 website


2009 JINR Prize winners
1 March 2010

The 2009 JINR Prize winners are announced. The first prize for applied research is awarded to LRB's scientists T.F. Fadeeva, O.V. Komova, E.A. Krasavin, L.A. Melnikova, E.A. Nasonova, and N.L. Shmakova for their work "Cytogenetic effects of low doses of ionizing radiation."

 


Winners of the Dynasty Foundation's 2009 contest for young physicists
1 March 2010

Alexander Bugay, an LRB scientist, is announced a winner of the Dynasty Foundation's 2009 program of support for young scientists holding a Candidate's degree. His project is concerned with non-linear oscillations and wave processes of different nature. One of the project's main aims is studying different aspects of the interaction of terahertz radiations with solids.

http://www.dynastyfdn.com/ (about the Dynasty Foundation)
http://www.dynastyfdn.com/news/568 (the winner list)


A talk by Prof. K.A. Trukhanov (Institute of Medical and Biological Problems)
26 February 2010

At a seminar held at the LRB, Prof. K.A. Trukhanov, a leading scientist of the Institute of Medical and Biological Problems, Russian Academy of Sciences, gave a talk entitled "A new method of the diagnostics of charged relativistic particle beams."


Elections of the LRB Deputy Directors
19 February 2010

Elections of the LRB Deputy Directors for Science were held at the 107th Session of the JINR Scientific Council. Two candidates were nominated: the present LRB Deputy Director for Science G.N. Timoshenko, Dr. Phys. and Math., and the Head of the Department of Education and Information at the National Center of Radiobiology and Radiation Protection (Sofia, Bulgaria) A. Yagova. Based on the voting results, the JINR Scientific Council appointed the candidates to the positions.


A seminar at the Laboratory of High Energy Physics
5 February 2010

Dr. Alla Boreyko, a leading scientist of the LRB, gave a talk entitled "Genetic effect of accelerated heavy ions" at a seminar at the Laboratory of High Energy Physics.

Abstract. Using JINR's basic facilities, the LRB has been conducting research on the genetic effect of accelerated heavy ions. The topicality of this research is connected with a number of important scientific and practical problems in radiation genetics, concerning the improvement of the methodology of the radiation therapy of cancer using accelerated carbon ions, and in space radiobiology. The radiation genetics issues involving the use of accelerated heavy ions in a wide range of linear energy transfer include molecular disorders in the structure of living cell DNA, induced mutation process, programmed cell death (apoptosis), radiation carcinogenesis, and modeling space radiation-induced genetic effects.


Report by the LRB Director to a session of the Committee of Plenipotentiaries
11 December 2009

On 16 21 November 2009, in Astana, the capital city of Kazakhstan, a circuit session was held of the Committee of Plenipotentiaries of the Governments of the JINR Member States. The Director of the Institute of Radiation Protection and Ecology of the Republic of Kazakhstan's National Nuclear Center Dr. S.N. Lukashenko and the LRB Director Prof. E.A. Krasavin presented a joint report on the problems of radioecology and radiobiology at the former Semipalatinsk nuclear test site entitled "The former Semipalatinsk nuclear test site and fundamental problems of radioecology and radiobiology." E.A. Krasavin spoke about the session results in his interview with the "Dubna" newspaper.


RIKEN Research: a letter by Prof. Kh. Kholmurodov
11 October 2009

In the latest issue of RIKEN Research in a special section for letters (postcards) from former visiting researchers about their time at RIKEN a letter by Prof. Kholmirzo Kholmurodov is published about his collaboration with RIKEN, Japan, including some group photos. The letter looks back on the long history of Prof. Kholmurodovs research ties with RIKEN, which he is happy to keep and develop.

Download RIKEN Research Vol. 4, Number 11, 2009.

Reference web pages:
https://www.rikenresearch.riken.jp/eng/postcard
https://www.rikenresearch.riken.jp/eng/postcard/6145
http://www.riken.jp/engn/index.html
http://www.rikenresearch.riken.jp/


NATO Advanced Training Course 'RADIPER'
25 October 2009

On 23 October 2009, the NATO Advanced Training Course on Rapid Diagnosis in Population at Emergency and Risk 'RADIPER' was closed in Krakow, Poland. The Joint Institute for Nuclear Research was represented by young members of staff of the Laboratory of Radiation Biology: Oleg Belov, a research fellow, and Elena Baranova, a laboratory assistant.

Brief information on the NATO advanced training course 'RADIPER'

Rapid Detection of Chemical, Biological, Radiological and Nuclear (CBRN) agents through chemical or physical dosimetry is usually precised but not always available. In such circumstances, rapid diagnosis with retrospective biological dosimetry can be crucial. Various methods of biodosimetry via the DNA and cytogenetic damage and their possible short and long term health effects on potentially exposed members of the population at risk were the main aims of the NATO Advanced Training Course on Rapid Diagnosis in Population at Emergency and Risk 'RADIPER.' As a result of violence, misfortune accident or any hostilities, inhabitants can be potentially exposed to hazardous chemicals or high doses of ionizing radiation that could cause direct clinical effects within days, weeks or years. Acute exposures to genotoxic agents can also result from natural environmental factors, non-specific contamination, the occupational environment, industrial discharges, and industrial accidents. A modern toxicology investigates a wide array of both old and new health hazards. Many methods are now available for monitoring humans and measuring genetic damage and other changes in macromolecules and body tissues. The RADIPER NATO advanced training course concentrated on the commonly measured biomarkers (chromosome aberrations; micronuclei; DNA damage), but others (p53 protein levels; metabolic genotypes) was also addressed. Distinguished scientists from the fields of toxicology, molecular biology, cytogenetics and epidemiology will present and discuss the state-of-the-art knowledge and recent developments in biological dosimetry and monitoring of population at risk.Rapid Detection of Chemical, Biological, Radiological and Nuclear (CBRN) agents through chemical or physical dosimetry is usually precised but not always available. In such circumstances, rapid diagnosis with retrospective biological dosimetry can be crucial. Various methods of biodosimetry via the DNA and cytogenetic damage and their possible short and long term health effects on potentially exposed members of the population at risk were the main aims of the NATO Advanced Training Course on Rapid Diagnosis in Population at Emergency and Risk "RADIPER." As a result of violence, misfortune accident or any hostilities, inhabitants can be potentially exposed to hazardous chemicals or high doses of ionizing radiation that could cause direct clinical effects within days, weeks or years. Acute exposures to genotoxic agents can also result from natural environmental factors, non-specific contamination, the occupational environment, industrial discharges, and industrial accidents. A modern toxicology investigates a wide array of both old and new health hazards. Many methods are now available for monitoring humans and measuring genetic damage and other changes in macromolecules and body tissues. The 'RADIPER' NATO advanced training course concentrated on the commonly measured biomarkers (chromosome aberrations; micronuclei; DNA damage), but others (p53 protein levels; metabolic genotypes) was also addressed. Distinguished scientists from the fields of toxicology, molecular biology, cytogenetics and epidemiology will present and discuss the state-of-the-art knowledge and recent developments in biological dosimetry and monitoring of population at risk.

Poster abstracts

Modeling of the induced mutation process in bacterial cells
O. Belov, E. Krasavin, A. Parkhomenko
A mathematical model of the mutation process in bacteria Escherichia coli induced by ultraviolet radiation is developed. Our model is based on the experimental data characterizing the main processes of the bacterial SOS response. Here we have modeled a whole sequence of the events leading to the fixation of the primary DNA lesion as a point mutation. A quantitative analysis of the key ways of the SOS mutagenesis was performed in terms of modern system biology. The dynamic changes of the basic SOS protein concentrations and the process of the translesion synthesis by the modified replication complex are described quantitatively. We have also demonstrated the applicability of the developed model to the description of the mutagenesis in individual genes. As an example, an estimation of the mutation frequency in E. coli's lacI gene is performed. The approaches to modeling of mutagenesis induced by ionizing radiation with different linear energy transfer are developed.

Evaluation of the influence of some factors on γ-induced apoptosis in human peripheral blood lymphocytes
E. Baranova, A. Boreyko, I. Ravnachka

In this work several experiments have been performed to study regularities in the induction of apoptotic cells in human lymphocytes by 60o γ-rays at different times after irradiation. Apoptotic index variability was detected in patients of different ages (21 62 years). Modifying effects have been studied of inhibitors of replicative and reparative DNA synthesis 1- β -D-arabinofuranosylcytosine (Ara-C) and hydroxyurea (Hu) on the kinetics of 60Co γ-rays induced apoptosis in human lymphocytes. It was shown that adding inhibitors results in the apoptotic cell output increasing during the post-irradiation period. Apoptosis induction by 60Co γ-rays in human lymphocytes in different cell cycle phases (G0, S, G1, and G2) has been studied. It was found that the apoptotic cell formation frequency in the beginning of the dose curve increases with the irradiation dose in all the cell cycle stages and then reaches a plateau. The maximal apoptosis output in lymphocyte cells was observed in the S phase.


5th International Summer School
22 July 2009

The Fifth International Summer School on Nuclear Physics Methods and Accelerators in Biology and Medicine is over. It was held in Bratislava on 6-15 July 2009. Scientists of the LRB and Dubna University students successfully presented their work.

Photo


Book by Prof. Kh.T. Kholmurodov "Molecular Simulation in Material and Biological Research"
21 July 2009

A new book edited by Prof. Kh T. Kholmurodov, "Molecular Simulation in Material and Biological Research," has been published by Nova Science Publishers Ltd (New York).

Summary

The book focuses on different aspects of molecular simulation in material and biological research; computational and theoretical studies of atomic and molecular interactions; and dynamics in between atoms, molecules, ions, clusters, and surfaces with emphasis on biomolecular protein simulation, including protein modeling; drug design; simulation of liquids; liquid crystals; polymer systems; simulation of radiation-induced damage and mutations; quantum biophysics; electronic structure of macromolecules; and parallel computing for chemical physics and biomolecular studies.

(Based on information at http://www.kriso.ee/)


Jubilee greetings
3 July 2009

Greetings to Prof. Kholmirzo Kholmurodov on the occasion of his 50th birthday!

Greetings from JINR Directorate 

Greetings from colleagues in Japan 

Greetings from rector of Tajik Technological University

The article published in "Omuzgor," a Newspaper of the Tajik Ministry of Education


8th Conference of Young Scientists, Specialists, and Students
15 April 2009

On 14 April 2009, the Institute of Medical and Biological Problems, Russian Academy of Sciences, held the 8th Conference of Young Scientists, Specialists, and Students timed to the Cosmonautics Day. The Conference program included a wide range of topical theoretical and applied issues in the safety as well as medical and biological aspects of space flights; human and animal physiology; cosmic, ecological, and extreme conditions medicine; hyperbaric physiology and diving medicine; psychophysiology; small group psychology; gravitational physiology; cosmic radiobiology; life support systems; sport medicine; and promising rocket and space systems and complexes. The Laboratory of Radiation Biology (LRB) was represented by O.V. Belov, V.N. Chausov, A.N. Kokoreva, S.I. Stukova, M.A. Tuchina, and I.I. Ravnachka. On the grounds of the Conference results, the first-place diploma was awarded to the LRB engineer Oleg Belov for his report entitled "Mathematical model of the ultraviolet irradiation-induced mutation process in bacterial cells Escherichia coli."
The conference site 

International youth conference "Education Without Borders 2009"
03 April 2009

On 29 March 1 April, the 5th International youth conference "Education without borders 2009" was held in Dubai, United Arab Emirates. The conference was concerned with approaches to the solution of modern global problems and prospects for the development of modern education systems. The Laboratory of Radiation Biology was represented by a poster report titled "Thermonuclear fusion is the future of humanity" by the engineer Oleg Belov.
The conference site

Changes in the structure of the Program Advisory Committee on Condensed Matter Physics
01 April 2009

An order has been signed on appointing the young staff member of the Laboratory of Radiation Biology Oleg Belov the scientific secretary of the Program Advisory Committee (PAC) on Condensed Matter Physics. The next PAC session will be held on 25 26 June 2009.

JINR Prize 2008
29 March 2009

The 2008 JINR Prize winners are announced. The Second Prize is awarded to a Laboratory of Radiation Biology team for a work cycle titled "Mechanisms of the mutation process in microorganisms under exposure to radiation with different physical characteristics." The authors are O.V. Belov, A.V. Boreiko, N.A. Koltovaya, E.A. Krasavin, and A.Yu. Parkhomenko.

Report to a meeting of the Committee of Plenipotentiaries of the JINR Member States
25 March 2009

On 27 28 March 2009, a meeting of the Committee of Plenipotentiaries of the JINR Member States was held at the International Conference Hall. As part of the meeting, the Director of the Laboratory of Radiation Biology Prof. E.A. Krasavin made a report titled "Radiobiological research at JINR's heavy ion accelerators: problems and prospects."

Video record taken at the conference "JINR Days in Hungary"
26 February 2009

A video record taken at the conference "JINR Days in Hungary" (3 7 December 2008, Budapest) is put up on our site.

 


13th Scientific Conference of the JINR Association of Young Scientists and Specialists
22 February 2009

On 16 22 February 2009, the 13th Scientific Conference of the JINR Association of Young Scientists and Specialists was held. The Laboratory of Radiation Biology was represented by three reports: O.V. Belov, "Modeling the induced mutation process in bacterial cells"; E.N. Lesovaya, "Calculation of a local neutron shielding for the gamma detector of an installation for detecting hidden drugs and explosives"; and E.M. Zaytseva, "Study of human cell response to irradiation by therapeutic proton beam." The reports by O.V. Belov and E.M. Zaytseva were awarded the Second Prize in the applied research and engineering category.
Conference site     Conference photos

Research and methodology seminar at the Veksler and Baldin Laboratory of High Energy Physics
18 February 2009

On 18 February 2009, a research and methodology seminar was held at the Veksler and Baldin Laboratory of High Energy Physics, where Prof. E.A. Krasavin gave a talk called "Radiobiology with accelerated heavy ions: problems and prospects." The talk aroused lively interest among specialists and was highly appraised by them.
 

General meeting of the Section of Biological Sciences, Russian Academy of Sciences
15 December 2008

On 15 December 2008, a general meeting of the Section of Biological Sciences, Russian Academy of Sciences, was held. It was concerned with a long-term forecast of the development of a number of fields in fundamental biology. Among the issues considered at the meeting was a proposal of the scientific and methodological supervision of the Laboratory of Radiation Biology (LRB), JINR., by the Section of Biological Sciences, Russian Academy of Sciences (SBS RAS). The LRB Director Prof. E.A. Krasavin presented a report on the LRB's research. The meeting supported a proposal of the scientific and methodological supervision of the LRB by the SBS RAS.


Conference in memory of Acad. O.G. Gazenko
12 December 2008

On 11 12 December 2008, the Russian Academy of Sciences held a conference marking the 90th anniversary of the birth of Acad. Oleg Gazenko (1918 2007) an outstanding scientist, one of the founders of cosmic biology and medicine. JINR was represented at the Conference by the JINR Director Acad. A.N. Sissakian and the LRB Director Prof. E.A. Krasavin.
The conference site     Article from weekly "Dubna" (in Russian)

JINR Days in Hungary
8 December 2008

On 3 7 December 2008, a workshop called "JINR Days in Hungary" was held in Budapest. The Laboratory of Radiation Biology was represented by its Director Prof. Evgeny Krasavin; he gave a talk entitled "Radiobiology with accelerated heavy ions: a new radiobiology." The report aroused lively interest among the conference participants. The conference booklet has been published.
Conference Program     Report abstract     Photo

Visit by Prof. Dr. Paras Prasad
2 December 2008

On 1 December 2008, Prof. Dr. Paras Prasad, a Professor of Chemistry of the State University of New York (SUNY) at Buffalo, who is participating in the Nanotechnology International Forum at the Expocenter Exhibition Complex in Moscow, visited the Laboratory of Radiation Biology (LRB). At Prof. P. Prasad's laboratory, the world's unique confocal laser microscope based on the coherent anti-Stokes Raman scattering techniques has been in operation in recent years. Another such microscope is going to be installed in April next year at the LRB. The LRB Director Prof. Evgeny Krasavin told Prof. Paras Prasad about the LRB's scientific fields and presented recent research results. Prof. P. Prasad showed great interest in the research performed at the LRB and expressed hope for cooperation between the LRB and SUNY at Buffalo.

Biophysical seminar
22 November 2008

On 21 November 2008, a seminar of the Laboratory of Radiation Biology was held. Ruben Arutyunyan, a Corresponding Member of the National Academy of Sciences, Armenia, presented a report "Individual sensitivity to radiation mutagenesis."


Biophysical seminar
20 November 2008

On 19 November 2008, a seminar of the Laboratory of Radiation Biology was held. Iva Jadrnickova of the Nuclear Research Institute, Rez (the Czech Republic), presented the following two reports: "Spatial distribution of absorbed dose on board the International Space Station"; "Dosimetry and LET spectrometry in C 290 MeV/n and Ne 400 MeV/n ion beams at HIMAC by different thermoluminescent detectors, track detectors, and Liulin detectors."


Plenary session of the Public Chamber of the Russian Federation
28 November 2008

On 27 November 2008, a plenary session of the Public Chamber of the Russian Federation was held on the topic "Nuclear medicine as an integral component of the medical care system of Russia." The Director of the Laboratory of Radiation Biology Prof. E.A. Krasavin participated in the session.


Third Annual Conference "Special Economic Zone of Dubna: First Steps"
22 November 2008

The Laboratory of Radiation Biology participated in the Third Annual Conference "Special Economic Zone of Dubna: First Steps," which was held on 20 21 November 2008 in the city of Dubna, the Moscow Region. The Director of the Laboratory Prof. E.A. Krasavin presented a report "Approaches to the development of new methods of the target therapy of cancer using gold nanoclusters and ultra high frequency radiation with high peak power."


Third round-table discussion of the NICA project
7 November 2008

On 5-6 November, the third round-table discussion of the NICA project "Searching for the Mixed Phase of Strongly Interacting Matter at the Nuclotron-based Ion Collider fAcility (NICA)" was held in Dubna. Its sessions took place at the Conference Hall of the Bogoliubov Laboratory of Theoretical Physics. As part of the conference, the Director of the Laboratory of Radiation Biology Prof. E.A. Krasavin presented a report "NICA as a powerful tool for a new radiobiology."

Round Table Program


Report to a Bureau Session of the Section of Biological Sciences, Russian Academy of Sciences
15 October 2008

On 14 October 2008, the Director of the Laboratory of Radiation Biology Prof. E.A. Krasavin presented a report to a Bureau Session of the Section of Biological Sciences, Russian Academy of Sciences: "Molecular and physiological mechanisms of the interaction between high-energy heavy ions and biological structures." The report aroused great interest in the issues concerned and was highly appreciated by specialists.

Report abstract


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